Doxycycline hyclate
CAS No.: 24390-14-5
Product Name: Doxycycline hyclate
CAS#24390-14-5
Spec: Veterinary Use
Package: 25kg/drum
Delivery time: one week
Dangerous goods or not: Not
Country of origin: China
CAS#24390-14-5
Spec: Veterinary Use
Package: 25kg/drum
Delivery time: one week
Dangerous goods or not: Not
Country of origin: China
Description
Spec of Doxycycline hyclate :
| Items | Specification | Results |
| Appearance | Yellow,hygroscopic,crystalline powder | Conforms |
| Solubility | Freely soluble in water and in methanol.sparingly solubleIn ethanol(96 per cent). It dissolves in solutions of alkalihydroxides and carbonates. | Conforms |
| Identification | HPLC | Conforms |
| Sulphuric acid reaction a yellow colour develops | Conforms | |
| It gives reaction of chlorides | Conforms | |
| pH | 2.0~3.0 | 2.4 |
| Specific Absorbance | At 349 nm E(1%) 300~335 | 320 |
| Specific optical rotation | -120°~-105° | -111° |
| Heavy metals | ≤50ppm | <50ppm |
| Light-absorbing impurities | At 490 nm <0.07 | 0.02 |
| Related substances | 6-epidoxycycline ≤2.0% | 1.7% |
| metacycline≤2.0% | 0.2% | |
| 4-epidoxycycline≤0.5% | not found | |
| 4-epi-6-epidoxycycline≤0.5% | not found | |
| oxytetracycline≤0.5% | not found | |
| 2-acety-2-decarbamoyldoxycycline≤0.5% | 0.4% | |
| any unspecified impurity≤0.1% | not found | |
| Ethanol | 4.3~6.0%(m/m) | 5.1% |
| Sulphated ash | ≤0.4% | 0.1% |
| Water | 1.4~2.8% | 2.0% |
| Assay | 95.0%~102.0%(C22H25CI2O8)(anhydrous and ethanol-free substance) | 96.1% |
